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Beta‐human chorionic gonadotropin‐positive extragonadal germ cell neoplasia of the renal pelvis
Author(s) -
Vahlensieck Winfried,
Riede Urs,
Ihling Christian,
Wimmer Berthold
Publication year - 1991
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19910615)67:12<3146::aid-cncr2820671235>3.0.co;2-g
Subject(s) - medicine , renal pelvis , human chorionic gonadotropin , germ cell tumors , gonadotropin , urology , pelvis , germ cell , gynecology , pathology , chemotherapy , surgery , hormone , ureter , biology , biochemistry , gene
A 56‐year‐old woman showed renal obstruction on the right side. Further examinations revealed a tumor of the renal pelvis. Nephroureterectomy on the right side was done. This extragonadal germ cell neoplasia had an immunohistochemically detected beta‐human chorionic gonadotropin (β‐hCG) expression. There were no other primary tumors or metastases. Although there were normal values after the operation, during the postoperative follow‐up, the serum β‐hCG temporarily reached 2400 IU/l and then dropped to normal without detection of metastases. No further therapy was given. The patient was alive and well 1 year and 10 months after surgery. To the authors' knowledge, this is the first extragonadal germ cell neoplasia of the renal pelvis with secretion of β‐hCG to the serum.