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Iodine‐125 interstitial implants as salvage therapy for recurrent gynecologic malignancies
Author(s) -
Sharma Sudarshan K.,
Isaacs John H.,
Forgione Hebe
Publication year - 1991
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19910515)67:10<2467::aid-cncr2820671013>3.0.co;2-k
Subject(s) - medicine , salvage therapy , iodine , surgery , chemotherapy , materials science , metallurgy
Twenty‐one patients with the diagnosis of recurrent gynecologic pelvic malignancy from various primary sites were treated with iodine‐125 (I‐125) interstitial implants. Eighteen of these patients had been treated with a combination of surgery and radiation therapy for their primary malignancies and 90% had responded. Seventy‐five percent had complete local responses. The overall survival time, volume–response relationship, and complications are discussed and the radioresponse of various histologic types is presented.