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Plasma cell granuloma of the nasal cavity treated by radiation therapy
Author(s) -
Seider Michael J.,
Frias Antonio,
Fuller Lillian M.,
Cleary Karen R.,
Van Tassel Pamela,
Alexanian Raymond,
Schantz Stimson P.
Publication year - 1991
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19910215)67:4<929::aid-cncr2820670412>3.0.co;2-q
Subject(s) - medicine , plasma cell granuloma , granuloma , nasal cavity , radiation therapy , plasma cell , surgery , presentation (obstetrics) , pathology , lesion , bone marrow , inflammatory pseudotumor
Plasma cell granuloma is a rare, benign tumor most commonly found in the lungs in patients younger than 30 years. Although presentation has been reported at a number of other anatomic sites, this report is the first of plasma cell granuloma of the nasal cavity. The tumor was initially resected, but progression was seen at 1‐month follow‐up. Because further surgery to completely eradicate the tumor would have been extensive and disfiguring, 40‐Gy external beam radiation was given in 20 fractions using a three‐field wedge technique. Most recent clinical follow‐up at 27 months showed local control. Surgery remains the treatment of choice for plasma cell granuloma when the disease can be completely resected. However, irradiation can also be effective in patients with recurrent or inoperable local disease.