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Hepatocellular carcinoma as second malignant neoplasms in successfully treated wilms' tumor patients. A National Wilms' Tumor Study report
Author(s) -
Kovalic Jeffrey J.,
Thomas Patrick R. M.,
Beckwith J. Bruce,
Feusner James H.,
Norkool Patricia A.
Publication year - 1991
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19910115)67:2<342::aid-cncr2820670204>3.0.co;2-y
Subject(s) - medicine , wilms' tumor , hepatocellular carcinoma , quadrant (abdomen) , pathology
Although rare, second malignant neoplasms (SMN) after treatment for Wilms' tumor are deadly. A recent National Wilms' Tumor Study (NWTS) report identified 15 patients with second malignancies discovered over 14,381 person‐years of observation. This report described four patients with secondary hepatocellular carcinoma in greater detail. These patients were strikingly similar in that all had right‐sided tumors and each one had received right upper‐quadrant irradiation. All patients died shortly after diagnosis of the SMN.