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Recovery of morphine from a controlled‐release preparation: A source of opioid abuse
Author(s) -
Crews James C.,
Denson Donald D.
Publication year - 1990
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19901215)66:12<2642::aid-cncr2820661229>3.0.co;2-b
Subject(s) - medicine , morphine , opioid , opioid related disorders , opioid abuse , drugs of abuse , anesthesia , medical emergency , opioid epidemic , psychiatry , addiction , receptor
MS‐Contin (Purdue‐Fredrick, Norwalk, CT) is a controlled‐release preparation of morphine sulfate that has demonstrated efficacy in the management of chronic cancer pain problems. It has recently come to the attention of the authors that MS‐Contin represents a potential source of opioid abuse through the extraction and intravenous injection of the morphine from this preparation. the authors describe a simple aqueous extraction method that was used to quantitatively determine the extent to which morphine could be obtained from MS‐Contin tablets.