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Surgical pathologic spread patterns of endometrial cancer: A gynecologic oncology group study
Author(s) -
Creasman William T.,
Morrow C. Paul,
Bundy Brian N.,
Homesley Howard D.,
Graham James E.,
Heller Paul B.
Publication year - 1987
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19901015)60:8+<2035::aid-cncr2820601515>3.0.co;2-8
Subject(s) - medicine , paraaortic lymph nodes , lymphadenectomy , hysterectomy , endometrial cancer , uterus , gynecologic oncology , carcinoma , stage (stratigraphy) , lymph node , metastasis , surgery , cancer , parametrium , surgical oncology , oncology , cervical cancer , paleontology , biology
The surgical pathologic features of 621 patients with Stage I carcinoma of the endometrium are presented. All patients were treated with primary surgery consisting of total abdominal hysterectomy, bilateral salpingo‐oophorectomy, selective pelvic and paraaortic lymphadenectomy and peritoneal cytology. An appreciable number of patients (144—22%) with Stage I cancers have disease outside of the uterus (lymph node metastasis, adenexal disease, intraperitoneal spread and/or malignant cells in peritoneal washings). Multiple prognostic factors particularly grade and depth of invasion are related to extrauterine disease. This study adds credence to the primary surgical approach with individualized postoperative therapy as indicated.