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Mammary ovarian metastases with stroma cell hyperplasia and postmenopausal virilization
Author(s) -
Caron Philippe,
Roche Henri,
Gorguet Bernadette,
Martel Pierre,
Bennet Antoine,
Carton Michel
Publication year - 1990
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19900915)66:6<1221::aid-cncr2820660623>3.0.co;2-b
Subject(s) - virilization , stroma , medicine , stromal cell , hyperplasia , hormone , pathology , gynecology , androgen , immunohistochemistry
The case of a 57‐year‐old woman with a history of breast cancer is reported. She presented 10 years later with virilization. Stroma cell hyperplasia was present in the metastatic ovaries. The authors describe hormonal data and discuss the pathogenesis of the stromal activity. Mammary ovarian metastases associated with stroma cell hyperplasia, in the absence of pregnancy, that cause virilization are rare.