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Cutaneous T‐cell lymphoma in a patient infected with human immunodeficiency virus type 1: Use of radiation therapy
Author(s) -
Goldstein Jeffrey,
Becker Norwin,
Delrowe John,
Davis Lawrence
Publication year - 1990
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19900915)66:6<1130::aid-cncr2820660609>3.0.co;2-0
Subject(s) - medicine , lymphoma , scalp , radiation therapy , biopsy , cutaneous t cell lymphoma , pneumonia , pathology , lesion , immunodeficiency , immune system , dermatology , mycosis fungoides , immunology , surgery
A patient with cutaneous T‐cell lymphoma (CTCL) and acquired immune deficiency syndrome (AIDS) is presented. The patient had a localized lesion on his scalp. Evaluation for systemic lymphoma was negative. A biopsy specimen showed superficial and deep dermal infiltrates of pleomorphic lymphocytes. Immunohistochemistry was consistent with T‐cell lymphoma. The patient was treated successfully with local irradiation. He remained free of further systemic and cutaneous recurrences of the lymphoma until he died 8 months after treatment of pneumonia. This case is the first to our knowledge to describe a localized CTCL in a patient infected with human immunodeficiency virus type 1 (HIV‐1).