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Chemotherapy as treatment of choice in extrapulmonary undifferentiated small cell carcinomas
Author(s) -
van der Gaast Ate,
Verwey Jaap,
Prins Eric,
Splinter Ted A. W.
Publication year - 1990
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19900201)65:3<422::aid-cncr2820650308>3.0.co;2-y
Subject(s) - medicine , chemotherapy , radiation therapy , carcinoma , oncology , small cell carcinoma , lung , survival rate , surgery
Extrapulmonary undifferentiated small cell carcinomas, especially those arising in the upper aerodigestive tract, form a group of neoplasms with a clinical behavior which resembles small cell carcinoma of the lung. In 11 patients treated by combination chemotherapy an objective response rate of 82% was achieved for a median duration of 8+ months. Median survival for all patients was 12 months. Long‐term survival was observed in those patients with limited disease who achieved a complete response after chemotherapy followed by radiotherapy.