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The molecular genetics of cancer.Introduction to principles of recombinant DNA technology
Author(s) -
Benz Edward J.
Publication year - 1990
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19900201)65:3+<731::aid-cncr2820651318>3.0.co;2-w
Subject(s) - gene , cancer , medicine , recombinant dna , genetics , computational biology , dna , biology , bioinformatics
There is now firm evidence that human cancers arise from derangements of a relatively restricted and well‐defined set of genes. I summarize the principles one must master in order to understand the mechanisms by which these genes disrupt normal regulation of cell growth.