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Islet cell carcinoma of the pancreas. A study of 98 patients
Author(s) -
Venkatesh Swamy,
Ordonez Nelson G.,
Ajani Jaffer,
Schultz Pamela N.,
Hickey Robert C.,
Johnston Dennis A.,
Samaan Naguib A.
Publication year - 1990
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19900115)65:2<354::aid-cncr2820650229>3.0.co;2-n
Subject(s) - medicine , pancreas , presentation (obstetrics) , disease , carcinoma , islet , gastroenterology , pancreatic disease , oncology , pathology , surgery , insulin
In 98 patients with histologically proved pancreatic islet cell carcinoma who were studied between 1950 and 1987, 55 had functioning tumors and 43 had nonfunctioning tumors. Both patient groups were compared in regard to age at presentation, metastases, and survival. Mean age at diagnosis was 51.1 years for the 55 men and 47 years for the 43 women. At diagnosis, 51 of the patients had regional disease and 47 had distant metastases. When matched for age, sex, and extent of disease, survival did not differ significantly in cases of functioning and nonfunctioning tumors. The patients' ages and the extent of disease at presentation were the most significant factors in prognosis and survival.