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Malignant transformation of benign cerebellar astrocytoma
Author(s) -
Schwartz Ann M.,
Ghatak Nitya R.
Publication year - 1990
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19900115)65:2<333::aid-cncr2820650225>3.0.co;2-3
Subject(s) - medicine , cerebellum , astrocytoma , malignant transformation , glioblastoma , pathology , cancer research
A patient who had a well‐differentiated cerebellar astrocytoma resected at 4 years of age, had glioblastoma multiforme of the cerebellum after a symptom‐free interval of 28 years. Late malignant transformation of a cerebellar astrocytoma of childhood is rare and previous cases are reviewed. Cerebellar astrocytomas are typically among the most benign of primary brain malignancies with excellent long‐term survival rates, sometimes with incomplete resection. This patient indicates that follow‐up needs to be long‐term because biologic behavior cannot be predicted fully in all cases.