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The istituto rizzoli experience with small cell osteosarcoma
Author(s) -
Bertoni F.,
Present D.,
Bacchini P.,
Pignatti G.,
Picci P.,
Campanacci M.
Publication year - 1989
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19891215)64:12<2591::aid-cncr2820641231>3.0.co;2-4
Subject(s) - medicine , osteosarcoma , osteoid , lesion , pathology , radiography , sarcoma , radiology
Osteosarcoma has been divided into numerous varieties based on clinical, radiographic, and histologic characteristics. Small cell osteosarcoma is a distinct subtype with a histologic appearance in which the bulk of the lesion is composed of round malignant cells with minimal areas of spindle cells. Osteoid production is always present. The lesion may mimic Ewing's tumor and other lesions in which round cells are seen. We report the clinical, radiologic, and pathologic features of this tumor, as well as the clinical outcome and response to therapy. Cancer 64:2591–2599, 1989.