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Has there been any improvement in the staging of gastric cancer?. Findings from the German gastric cancer TNM study group
Author(s) -
Rohde Henning,
Gebbensleben Brigitte,
Bauer Peter,
Stützer Hartmut,
Zieschang Jürgen
Publication year - 1989
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19891215)64:12<2465::aid-cncr2820641212>3.0.co;2-y
Subject(s) - medicine , stage (stratigraphy) , cancer , surgery , stomach , gastroenterology , carcinoma , paleontology , biology
This multicenter observational study examined the survival of 1420 patients with histologically proven carcinoma of the stomach. From April 1982 through October 1984, 1360 (95%) patients underwent surgery, 988 (72%) had resections, and 372 (28%) minor surgical procedures. The percentage of patients who have been followed until death or 3 to 5 years was 99.4%. Patients were staged preoperatively and intraoperatively and by pathologists using the old (1978) and new (1987) TNM stage groupings and 5‐year survival was analyzed. Subgroups of patients who changed their stage group according to the new stage definitions were analyzed separately. Only age was an important prognostic factor for survival in Stage IA (P < 0.05) and Stage IB (P < 0.01). Residual tumor after surgery was most important for survival in Stage I1 (P < 0.01) and Stage IIIA (P < 0.001). This indicates that improvements of stage definitions for individual prognosis can only be achieved by adding data concerning the presence or absence of residual tumor (R classification). Cancer 64:2465–2481, 1989.