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High‐grade B‐cell lymphoma presenting as polyserosal disease. Diagnosis by flow cytometry
Author(s) -
Moreb Jan,
Duque Ricardo E.,
Siddiqui Tarique,
McCarley Dean L.,
Braylan Raul C.
Publication year - 1989
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19891201)64:11<2254::aid-cncr2820641112>3.0.co;2-i
Subject(s) - medicine , anasarca , lymphoma , flow cytometry , immunophenotyping , pathology , differential diagnosis , presentation (obstetrics) , immunology , radiology
Two patients presenting with anasarca were found to have aggressive B‐cell lymphoma. No bulky disease was detected. The diagnosis was rapidly established by the flow cytometric analysis of cell surface immunophenotype and cell cycle fractions of pleural or peritoneal cells. Such presentation of lymphoma is unusual and previously undescribed, and it may have a significant negative prognostic impact. The authors' observations indicate that lymphoma be included in the differential diagnosis of anasarca and that flow cytometry can be useful for a fast confirmation of the diagnosis.