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Excisional biopsy as the first therapeutic procedure versus primary wide excision of malignant melanoma
Author(s) -
Landthaler Michael,
BraunFalco Otto,
Leitl August,
Konz Birger,
Hölzel Dieter
Publication year - 1989
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19891015)64:8<1612::aid-cncr2820640810>3.0.co;2-7
Subject(s) - medicine , biopsy , melanoma , surgery , wide local excision , surgical excision , radiology , cancer research
The five‐year disease‐free rate (5‐y‐DFR) and five‐year survival rate (5‐y‐SR) of 319 melanoma patients with a narrow excisional biopsy in local anesthesia as the first procedure followed by delayed wide excision, were compared with 5‐y‐DFR and 5‐y‐SR of 635 primary radically treated patients. Five‐y‐DFR and 5‐y‐SR did not differ in either group of patients. Furthermore, the time interval (≤21 days versus > 21 days) between excisional biopsy and delayed wide excision had no influence on the outcome of the patients. Based on the results of the study and the literature, excisional biopsy of malignant melanoma followed by delayed wide excision is a safe procedure.