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Prognostic factors in mobile tongue and floor of mouth carcinoma
Author(s) -
Brown Bert,
Barnes Leon,
Mazariegos Juan,
Taylor Floyd,
Johnson Jonas,
Wagner Robin L.
Publication year - 1989
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19890915)64:6<1195::aid-cncr2820640606>3.0.co;2-7
Subject(s) - medicine , floor of mouth , perineural invasion , tongue , basal cell , tongue neoplasm , carcinoma , cancer , pathology , radiology
This study identifies significant prognostic factors in squamous cell carcinomas of the anterior tongue and floor of mouth. It is clear that the TMN staging system does not account for other important variables that affect tumor prognosis. Tumor thickness and the presence of perineural invasion and intralymphatic tumor emboli should be examined in all resected tumors. Tumor thickness, tumor size, and perineural invasion all have an impact on survival and must be considered in treatment plans. Tumors measuring between 2 mm and 3 mm may or may not have metastases and further evaluation of this group needs to be done. Most importantly, the data in this study supports a multiinstitutional prospective evaluation of pathology specimens. Precise guidelines must be established for handling of the specimen, which must then be evaluated for the variables mentioned above. In this way, more definitive conclusions can be reached in the management of tumors of the antierior tongue and floor of mouth.