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Duodenal gangliocytic paraganglioma with lymph node metastasis in a 17‐year‐old boy
Author(s) -
Inai Kouki,
Kobuke Toshihiro,
Yonehara Shuji,
Tokuoka Shoji
Publication year - 1989
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19890615)63:12<2540::aid-cncr2820631231>3.0.co;2-h
Subject(s) - histogenesis , medicine , pathology , enolase , immunohistochemistry , paraganglioma , metastasis , ganglion , lymph node , lymph node metastasis , anatomy , cancer
A case of duodenal gangliocytic paraganglioma (DGP) in a 17‐year‐old boy is presented. In this case a lymph node in the peripancreatic region was involved by a metastatic tumor. A review of the literature on DGP indicates that this case represents the youngest patient and is the second case of DGP with metastasis. Immunohistochemical staining for neuron‐specific enolase (NSE), neurofilament (NF), pancreatic polypeptide, and somatostatin showed positive results for epithelioid and ganglion‐like cells, whereas spindle cells showed immunoreactivities for S‐100 protein, NSE, and NF. The histogenesis of DGP is discussed.