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Malignant schwannoma of the clitoris in a 1‐year‐old child
Author(s) -
Thomas William J.,
Bevan Herbert E.,
Hooperm Dennis G.,
Downey Earl J.
Publication year - 1989
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19890601)63:11<2216::aid-cncr2820631126>3.0.co;2-8
Subject(s) - medicine , neurofibromatosis , clitoris , vincristine , schwannoma , cyclophosphamide , chemotherapy , surgery , radiology
A 1‐year‐old infant with von Recklinghausen' neurofibromatosis was seen because of increasing clitoral enlargement over a 7‐month period. The mother, who also had neurofibromatosis, was treated 2 years beforehand for an acoustic neuroma. The child was treated by radical clitorectomy. Pathologic examination revealed malignant schwannoma, a tumor not previously described in this site. Vincristine, dactinomycin, and cyclophosphamide chemotherapy was given for 2 years to prevent local recurrence and metastatic spread. The child remains tumor free 25 years after diagnosis.