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Chemotherapy in the management of intraocular lymphoma
Author(s) -
Strauchen James A.,
Dalton Jack,
Friedman Alan H.
Publication year - 1989
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19890515)63:10<1918::aid-cncr2820631008>3.0.co;2-d
Subject(s) - medicine , intraocular lymphoma , lymphoma , chemotherapy , radiation therapy , refractory (planetary science) , surgery , physics , astrobiology
Six patients with intraocular (vitreous) lymphomas were treated with high‐dose intravenous cytosine arabinoside (Ara‐C). Four patients were previously untreated, one patient had previously received ocular and central nervous system radiation therapy and relapsed, and one patient had previously received chemotherapy for systemic lymphoma. Five responses were observed: one complete and four partial. High‐dose Ara‐C is active in intraocular (vitreous) lymphoma, but complete response is uncommon. Adjunctive use of Ara‐C in combination with ocular irradiation may be a useful form of therapy in this uncommon lymphoma.