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Binding of soybean agglutinin lectin to prostatic hyperplasia and adenocarcinoma
Author(s) -
Loy Timothy S.,
Kyle Judy,
Bickel John T.
Publication year - 1989
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19890415)63:8<1583::aid-cncr2820630823>3.0.co;2-k
Subject(s) - hyperplasia , medicine , immunoperoxidase , lectin , pathology , soybean agglutinin , agglutinin , adenocarcinoma , atypical hyperplasia , cancer , immunology , monoclonal antibody , antibody
The binding of soybean agglutinin (SBA) lectin to routinely processed surgical pathology material from cases of prostatic hyperplasia, atypical hyperplasia, and adenocarcinoma was studied using an immunoperoxidase technique. Positive staining was obtained in eight of eight cases of nodular hyperplasia, eight of eight cases of atypical hyperplasia, and ten of 11 cases of adenocarcinoma. This report indicates that this lectin is not useful in distinguishing prostatic hyperplasia from adenocarcinoma.