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Patterns of the first lymph node metastases in patients with cutaneous malignant melanoma of axial localization
Author(s) -
LockAndersen J.,
Partoft S.,
Jensen M. G.
Publication year - 1988
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19881101)62:9<2073::aid-cncr2820620934>3.0.co;2-i
Subject(s) - medicine , lymph node , melanoma , trunk , primary tumor , lymphatic system , head and neck , lymph , radiology , metastasis , surgery , cancer , pathology , ecology , cancer research , biology
At the Finsen Institute, Copenhagen, from 1971 to 1981, 134 patients were treated for lymph node metastases from primary cutaneous malignant melanoma of axial localization ( e.g. , in the head and neck and trunk), where metastases to regional lymph node groups were the first sign of dissemination. Due to the lack of sufficient clinical data, 27 patients were excluded from the study. Median time from excision of primary tumor to diagnosis of node metastases was 11 months. in 42 of 85 (49%) patients with tnincal melanoma, the primary tumor was placed in the lymphatic water‐shed areas. Two patients among this group showed bilateral simultaneous metastases to two different node groups. in the remaining 43 patients with tnincal tumors located outside water‐shed areas, node metastases developed in unexpected groups in seven (16%) patients. of 22 patients with head and neck tumors, two (9%) patients demonstrated metastases to distant lymph node groups without metastases to the regional node basins.