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Primary rhabdomyosarcoma of the kidney: A light microscopic, immunohistochemical, and electron microscopic study
Author(s) -
Grig David J.,
McIsaac Gary P.,
Armstrong Ross F.,
Wyatt John K.
Publication year - 1988
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19881101)62:9<2027::aid-cncr2820620926>3.0.co;2-6
Subject(s) - medicine , pathology , immunoperoxidase , rhabdomyosarcoma , immunohistochemistry , sarcoma , renal cell carcinoma , kidney , population , antibody , environmental health , immunology , monoclonal antibody
Primary rhabdomyosarcoma of the kidney is a rare and highly aggressive tumor in the adult population. A case is reported in a 70‐year‐old woman with the diagnosis confirmed by immunohistochemistry and electron microscopy. This is the first case studied using the immunoperoxidase technique and the second with electron microscopic examination. To make a diagnosis of primary sarcoma, of the kidney, three criteria must be met: (1) a metastatic sarcoma must be ruled out; (2) the tumor must arise from renal parenchyma; and (3) a sarcomatoid variant of renal cell carcinoma needs to be excluded. The literature is reviewed and available clinical and pathologic details are summarized.