Premium
Soluble immune complexes and squamous cell carcinoma‐related antigens in patients with head and neck cancer
Author(s) -
Yamanaka Noboru,
Himi Tetsuo,
Harabuchi Yasuaki,
Hoki Katsuhumi,
Kataura Akikatsu
Publication year - 1988
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19881101)62:9<1932::aid-cncr2820620911>3.0.co;2-a
Subject(s) - medicine , head and neck cancer , antigen , cancer , radioimmunoassay , immune system , head and neck squamous cell carcinoma , immunoassay , basal cell , head and neck , nasopharyngeal carcinoma , oncology , stage (stratigraphy) , hypopharyngeal cancer , antibody , immunology , radiation therapy , surgery , paleontology , biology
Sera from 85 patients with head and neck cancer including laryngeal cancer, hypopharyngeal cancer, nasopharyngeal cancer, and maxillary cancer were assayed for immune complexes (1C) by solid‐phase anti‐C3 enzyme immunoassay and for squamous cell carcinoma‐related (SCC) antigen by radioimmunoassay. The positive rates of 1C and SCC antigen in head and neck cancer patients were 29.4% and 34.1%, respectively. Their serum levels and positive rates were found to be elevated according to the degree of advancement of the disease stage, showing their good clinical correlations. With individual patients there was no significant relationship between 1C and SCC antigen.