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Primary retroperitoneal pure choriocarcinoma. Two long‐term complete responders from a rare fatal disease
Author(s) -
Moss Jerry F.,
Slayton Robert E.,
Economou Steven G.
Publication year - 1988
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19880915)62:6<1053::aid-cncr2820620605>3.0.co;2-y
Subject(s) - choriocarcinoma , medicine , germ cell tumors , germ cell , disease , oncology , rare disease , chemotherapy , biology , biochemistry , gene
Extragonadal germ cell tumors may have a worse prognosis than germ cell tumors of gonadal origin, even when tumor bulk and extent of dissemination are equal. Primary retroperitoneal pure choriocarcinoma is one of the least common subgroups of the extragonadal germ cell tumors and has previously appeared to have the worst prognosis. Two new case reports on the treatment and follow‐up of two patients with primary retroperitoneal pure choriocarcinoma are discussed. Both patients are diseasefree at 24 and 81 months, respectively. After aggressive primary multiagent drug therapy for primary retroperitoneal pure choriocarcinoma, a favorable prognosis may be anticipated.