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Carcinoma of the bronchus with unsuspected microscopic resection‐line involvement
Author(s) -
Whyte Md Richard I. ,,
Kaplan David K.,
Sharpe David A. C.,
Muehrcke Md Derek D. ,,
Donnelly Raymund J.
Publication year - 1988
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19880901)62:5<1014::aid-cncr2820620529>3.0.co;2-1
Subject(s) - medicine , bronchus , carcinoma , resection , radiology , surgery , pathology , respiratory disease , lung
In a series of 560 pulmonary resections for bronchial carcinoma, unsuspected microscopic tumor was present at the bronchial resection margin in 26 patients (4.5%). Adjuvant chemotherapy or radiotherapy was given in two patients. In follow‐up times ranging from 1 to 72 months (mean, 22 months), 58% of patients were alive and free of recurrent disease. Twelve patients underwent periodic surveillance bronchoscopy in an attempt to identify early local recurrence. Eighty‐three percent of these patients were alive and disease‐free in follow‐up times from 4 to 72 months (mean, 29.7 months). Only one patient developed local recurrence and presented with hemoptysis between routine surveillance bronchoscopies. It was concluded that microscopic residual resection‐line tumor does not preclude prolonged survival and that no benefit from surveillance bronchoscopy could be demonstrated in this small patient sample.