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Spontaneous regression of a small non‐cleaved cell malignant lymphoma (Non‐burkitt's lymphoblastic lymphoma). Morphologic, immunohistological, and immunoglobulin gene analysis
Author(s) -
Poppema Sibrand,
Postma Liedeke,
Brinker Marja,
De Jong Bauke
Publication year - 1988
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19880815)62:4<791::aid-cncr2820620425>3.0.co;2-m
Subject(s) - medicine , lymphoma , immunoglobulin gene , pathology , lymphoblastic lymphoma , lymph node , biopsy , antibody , tonsil , malignant lymphoma , immunology , t cell , immune system
Complete spontaneous regression of high‐grade malignant non‐Hodgkin's lymphoma is extremely unusual. In this report the authors describe a complete spontaneous remission after surgical excisional biopsy of a small noncleaved cell malignant lymphoma (non‐Burkitt's lymphoblastic lymphoma) of the tonsil in a 12‐year‐old boy. The diagnosis was confirmed by immunohistologic and immunoglobulin gene analysis. Similar studies were performed on the cervical lymph node excised 2 weeks later when spontaneous remission had occurred. The patient has remained in good health for over 3 years.