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Multiple reoperations in recurrent colorectal carcinoma. An analysis of morbidity, mortality, and survival
Author(s) -
Sardi Armando,
Minton John Peter,
Nieroda Carol,
SickleSantanello Brenda,
Young Donn,
Martin Edward W.
Publication year - 1988
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19880501)61:9<1913::aid-cncr2820610932>3.0.co;2-y
Subject(s) - medicine , surgery , carcinoma , colorectal cancer , complication , prospective cohort study , survival rate , survival analysis , cancer
Fifty‐eight patients in an existing prospective study were evaluated to determine if multiple reoperations for recurrent colorectal carcinoma extended survival. All patients had at least three major operative procedures. The median survival from first, second, third, fourth, and fifth recurrence was 29.9, 17.3, 16, 12.3, and 7.2 months, respectively. The median postoperative hospital stay was 11 days, with a range of 1 to 96 days. The major complication rate was 17%. Twenty‐one patients are still alive 19 to 140 months from diagnosis (mean, 50.3 months), 9 to 125 months from the first recurrence (mean, 31.1 months), and 5 to 109 months (mean, 22 months) from the second recurrence. Eleven patients have no evidence of disease. Reoperation for recurrent colorectal carcinoma can be done with acceptable morbidity and mortality and an increase in survival.