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Peripheral T‐cell lymphoma in a patient with acquired immune deficiency syndrome
Author(s) -
Nasr Sherif A.,
Brynes Russell K.,
Garrison Charles P.,
Chan Wing C.
Publication year - 1988
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19880301)61:5<947::aid-cncr2820610515>3.0.co;2-g
Subject(s) - medicine , lymphoma , immune system , immunology , context (archaeology) , virus , antibody , t cell , immunopathology , biology , paleontology
A case of pulmonary T‐cell lymphoma in an Acquired Immune Deficiency Syndrome (AIDS) patient is presented. Morphologically, it belonged to the large cell, immunoblastic category of the Working Formulation and demonstrated a helper/inducer phenotype. Clinically there was no association with manifestations of human T‐lymphotropic virus (HTLV)‐I related lymphoma and the patient was seronegative for HTLV‐I and HTLV‐II antibodies. High‐grade B‐cell lymphomas occur with an increased frequency in patients with AIDS but the occurrence of a peripheral T‐cell lymphoma in AIDS has not been documented before. The case is discussed in the context of current concepts of AIDS‐related lymphomagenesis.