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Dedifferentiated liposarcoma of the liver
Author(s) -
Kim Yong Il,
Yu Eun Sil,
Lee Keun Wook,
Park Eui U,
Song Hyung Geun
Publication year - 1987
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19871201)60:11<2785::aid-cncr2820601131>3.0.co;2-o
Subject(s) - medicine , liposarcoma , general surgery , pathology , sarcoma
Among the rare occurrences of primary malignant mesenchymal tumors of the liver, the development of liposarcoma has been only theoretically listed—there is no proven example in the literature. This article documents a case of primary liposarcoma of the liver in a 30‐year‐old woman who presented with a huge intrahepatic tumor in the left lobe measuring 14 × 10 × 6 cm. It was composed of two distinct macroscopic and histologic features—the well‐differentiated liposarcoma and the cellular, nonlipogenic pleomorphic sarcoma. The former was a mature, lipomatous tumor with various stages of lipoblasts. The latter was much more cellular, made up of pleomorphic cells admixed with a few areas of spindle cells with many mitotic figures, resembling a pleomorphic variant of malignant fibrous histiocytoma. Oil red O stain revealed multifocal, but a scanty amount, of fat‐storing tumor cells in both compartments aside from large fat globules in the differentiated area. This is the first reported case of primary liposarcoma of the liver.