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Effective chemotherapy for small cell carcinoma of the esophagus
Author(s) -
Tanabe Gen,
Kajisa Takashi,
Shimazu Hisaaki,
Yoshida Aichi
Publication year - 1987
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19871201)60:11<2613::aid-cncr2820601106>3.0.co;2-s
Subject(s) - medicine , esophagus , chemotherapy , carcinoma , oncology , small cell carcinoma , general surgery
This article documents the use of chemotherapy in a case of small cell carcinoma of the esophagus with multiple liver and lymph node metastases. A multi‐drug regimen was used and included cisdichlorodiamine platinum (CDDP), VP‐16, vincristine (VCR), adriamycin (ADM), and cyclophosphamide (CPA). After chemotherapy, the esophageal tumor disappeared, and liver masses reduced in number and degenerated. Nine months later, however, the patient died of brain metastases. It was concluded that radiotherapy should be given to the brain for the prophylaxis of tumor relapse.