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Prognostic factors for gastrointestinal and bronchopulmonary carcinoid tumors
Author(s) -
Greenberg Raymond S.,
Baumgarten Deborah A.,
Clark W. Scott,
Isacson Peter,
McKeen Kathleen
Publication year - 1987
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19871115)60:10<2476::aid-cncr2820601022>3.0.co;2-r
Subject(s) - medicine , malignancy , stage (stratigraphy) , carcinoid tumors , gastroenterology , univariate analysis , gastrointestinal cancer , multivariate analysis , large intestine , cancer , population , colorectal cancer , paleontology , environmental health , biology
Data collected by population‐based cancer registries in Iowa and metropolitan Atlanta were evaluated to determine prognostic factors for gastrointestinal (n = 270) and bronchopulmonary (n = 151) carcinoids. The predictors considered in univariate and multivariate analyses were: age, sex, race, marital status, anatomic subsite, stage, occurrence of other malignancies, and surgery. For surgically treated gastrointestinal tumors, the cumulative percentages of survivors at five years were: appendix, 85.6%; small intestine, 66.0%; and large intestine, 37.7%. The likelihood of death from gastrointestinal carcinoids was found to be related independently to increasing age ( P = 0.001), advanced stage ( P < 0.0001), location within the large intestine ( P < 0.0001), and occurrence of another malignancy ( P = 0.02). The overall five‐year survival rate for bronchopulmonary carcinoids was 87.6%, and lack of surgical treatment ( P < 0.0001) and advanced stage ( P = 0.006) were associated independently with unfavorable prognosis.