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A new technique to protect ovarian function before pelvic irradiation: Heterotopic ovarian autotransplantation
Author(s) -
Leporrier Michel,
Von Theobald Peter,
Roffe JeanLuc,
Muller Georges
Publication year - 1987
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19871101)60:9<2201::aid-cncr2820600915>3.0.co;2-z
Subject(s) - autotransplantation , ovary , medicine , pelvic cavity , radiation therapy , transplantation , fertility preservation , premature ovarian failure , surgery , ovarian tissue cryopreservation , ovarian tissue , follicle , fertility , gynecology , population , environmental health
The authors describe a new technique for the subcutaneous heterotopic transplantation of the ovary before pelvic irradiation to treat Hodgkin's disease. Creation of a cavity to receive the transplant and the use of two surgical teams and the surgical microscope during the operation ensured its successful outcome. The transplanted ovary was, followed up clinically and by ultrasound monitoring: ovarian cycles remained regular despite radiotherapy, and follicle growth occurred normally. In comparison to other types of oophoropexy described in the literature, the advantages of this technique included total protection of the ovary from irradiation, and conservation of ovarian function and fertility. One year after the procedure, puncture of the ovarian compartment produced a mature oocyte specimen.