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Angioimmunoblastic lymphadenopathy with dysproteinemia: Complete remission with cisplatin‐based chemotherapy
Author(s) -
Uphouse William J.,
Woods Joseph C.
Publication year - 1987
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19871101)60:9<2161::aid-cncr2820600907>3.0.co;2-r
Subject(s) - medicine , prednisone , chemotherapy , cisplatin , pneumonia , disease , combination chemotherapy , dermatology
Angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) is classified as a nonmalignant condition, yet the mortality associated with the disease rivals most malignancies. Although a leading standard text recommends prednisone as initial management, there has been increasing evidence that combination chemotherapy is the best initial treatment. The patient described here achieved a complete remission with cisplatin‐based therapy but later died of pneumonia, perhaps because pathogens important in infections in AILD were not covered. Specific recommendations for management are discussed.