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Multiple malignant rectal carcinoid tumors with immunocytochemical demonstration of multiple hormonal substances
Author(s) -
Kanter Michael,
Lechago Juan
Publication year - 1987
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19871015)60:8<1782::aid-cncr2820600819>3.0.co;2-t
Subject(s) - argentaffin , medicine , rectum , somatostatin , carcinoid tumors , immunocytochemistry , pathology , hormone
This case report deals with a patient who presented with 17 small carcinoid tumors of the rectum, the largest measuring less than 1 cm in diameter. After a review of the literature on this subject, this case is believed to be highly unusual in several respects: (1) despite their small size, these tumors resulted in multiple metastases to the regional lymph nodes; (2) both primary tumors and metastases were extensively and strongly argentaffin; and (3) most tumors and metastases contained, when investigated by immunocytochemistry, several biologically active substances such as serotonin, somatostatin, and glucagon‐like immunoreactivity.