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Intrapericardial yolk sac tumor in an infant girl
Author(s) -
Nelson Edward,
Stenzel Peter
Publication year - 1987
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19871001)60:7<1567::aid-cncr2820600726>3.0.co;2-a
Subject(s) - medicine , yolk sac , endodermal sinus tumor , girl , resection , surgery , chemotherapy , heart failure , radiology , cardiology , embryo , psychology , developmental psychology , germ cell tumors , biology , microbiology and biotechnology
Abstract This article is a report on the first known case of an intrapericardial yolk sac (endodermal sinus) tumor discovered in a 14‐month‐old girl. The patient presented with a systolic murmur, cardiomegaly, and manifestations of cardiac failure. At surgery a large, friable, intrapericardial mass with no evidence of extrapericardial spread was found. Histologic and immunohistochemical findings were diagnostic of yolk sac tumor. Following initial resection, chemotherapy, and a second resection 13 months after the first, the patient died 24 months after diagnosis. Tumor enlargement was associated with elevated serum alpha‐fetoprotein levels.