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Successful treatment with chemotherapy and subsequent allogeneic bone marrow transplantation for myeloid blastic crisis of chronic myelogenous leukemia following advanced Hodgkin's disease
Author(s) -
Punt Cornelis J. A.,
RozenbergArska Maja,
Verdonck Leo F.
Publication year - 1987
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19870901)60:5<934::aid-cncr2820600503>3.0.co;2-y
Subject(s) - medicine , chronic myelogenous leukemia , chemotherapy , myeloid leukemia , disease , leukemia , radiation therapy , bone marrow , transplantation , incidence (geometry) , myeloid , oncology , physics , optics
A 33‐year‐old man was treated with intensive chemotherapy for myeloid blastic crisis of chronic myelogenous leukemia (CML), which developed after radiotherapy and chemotherapy for Hodgkin's disease. After achieving a second chronic phase, he underwent allogeneic bone marrow transplantation (BMT). Despite many complications, 1 year after BMT the disease was in complete remission and the patient was in excellent condition. The incidence of CML following treatment for Hodgkin's disease is briefly discussed. This is the first report of prolonged complete remission for blastic crisis of CML, which developed after combined treatment for advanced Hodgkin's disease.