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Metastatic hemangiopericytoma with prolonged survival
Author(s) -
Hart Lowell L.,
Weinberg J. Brice
Publication year - 1987
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19870815)60:4<916::aid-cncr2820600434>3.0.co;2-o
Subject(s) - medicine , hemangiopericytoma , vincristine , cyclophosphamide , methotrexate , primary tumor , doxorubicin , chemotherapy , lung , surgery , oncology , pathology , metastasis , cancer
A case of a hemangiopericytoma tumor metastatic to the lung from a central nervous system primary tumor in the posterior fossa is reported. The tumor was not responsive to treatment with cyclophosphamide, Adriamycin (doxorubicin), vincristine, DTIC (CYVADIC), high‐dose methotrexate with citro‐vorum factor rescue, aziridinobenzoquinone (AZQ), or dibromodulcitol. However, the patient has had a prolonged survival, lasting for more than 26 years from original diagnosis, despite extensive recurrent primary disease and massive pulmonary metastases. Clinical and pathologic characteristics of these tumors are reviewed, with emphasis on the potential for long‐term survival.