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Invasive bladder carcinoma. The importance of initial transurethral surgery and other significant prognostic factors for improved survival with full‐dose irradiation
Author(s) -
Shipley William U.,
Prout George R.,
Kaufman S. Donald,
Perrone Terresa L.
Publication year - 1987
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19870801)60:3+<514::aid-cncr2820601513>3.0.co;2-m
Subject(s) - medicine , cystectomy , radiation therapy , bladder cancer , retrospective cohort study , carcinoma , chemotherapy , surgery , disease , urology , cancer
This review covers recent observations (all retrospective) on useful prognostic indicators in patients treated by radiation for this heterogeneous disease, including presenting clinical characteristics, extent of conservative surgery, radiographic studies, and pathologic subtypes. Although imperfect and incomplete, this review offers some criteria to identify which patients will do well and which quite poorly if treated by bladder‐preserving full‐dose radiation therapy. Such criteria should help clinicians recommending full‐dose radiation therapy, radical cystectomy, or innovative combinations of chemotherapy, radiation, and surgery.