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Analysis of prognostic factors in patients with isolated chest wall recurrence of breast cancer
Author(s) -
Magno Lorenzo,
Bignardi Mario,
Micheletti Enrico,
Bardelli Donata,
Plebani Franco
Publication year - 1987
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19870715)60:2<240::aid-cncr2820600221>3.0.co;2-9
Subject(s) - medicine , breast cancer , mastectomy , stage (stratigraphy) , disease , surgery , retrospective cohort study , mammary gland , oncology , cancer , paleontology , biology
A retrospective analysis of a series of 162 patients treated for isolated chest wall recurrence of breast cancer after mastectomy was undertaken. Cumulative survival, distant relapse‐free survival, and freedom from local progression after 5 years from the diagnosis of recurrence were 34%, 28%, and 45% respectively. Five prognostic factors influenced survival: axillary node status, primary T stage, length of disease‐free interval, and number and size of recurrences. Four prognostic factors influenced the local control: axillary node status, primary T stage, disease‐free interval, and number of recurrences. Patients with three or more, out of five, favorable prognostic factors fared much better than those with two or less: 75% versus 15% survival at 5 years. Our findings suggest that it is possible to identify a group of patients with a distinctly good medium‐term survival and local control of disease.