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Malignant struma ovarii treated by ovariectomy, thyroidectomy, and 131 I administration
Author(s) -
Willemse P. H. B.,
Oosterhuis J. W.,
Aalders J. G.,
Piers D. A.,
Sleijfer D. Th.,
Vermey A.,
Doorenbos H.
Publication year - 1987
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19870715)60:2<178::aid-cncr2820600210>3.0.co;2-q
Subject(s) - medicine , struma ovarii , thyroglobulin , thyroid , histopathology , pathology , thyroidectomy , ovary , scintigraphy
A 36‐year‐old woman presented with an intraperitoneally disseminated malignant struma ovarii, diagnosed by histopathology and 131 I scintigraphy. The serum thyroglobulin level was elevated, and immunoperoxidase staining for thyroglobulin was positive for disease both in the tumor cells lining the follicles and in the colloid. The patient was treated successfully by a bilateral ovariectomy followed by a total thyroidectomy and administration of radioactive iodine. The clinical behavior and the presence of thyroglobulin in both serum and tumor tissue demonstrate the similarity between neoplastic thyroid tissue in the ovary and in the thyroid gland.