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Synovial sarcomas true carcinosarcomas?
Author(s) -
Leader Mary,
Patel J.,
Collins M.,
Kristin Henry
Publication year - 1987
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19870615)59:12<2096::aid-cncr2820591222>3.0.co;2-c
Subject(s) - synovial sarcoma , histogenesis , pathology , medicine , cytokeratin , carcinosarcoma , vimentin , mesenchymal stem cell , sarcoma , antibody , immunohistochemistry , carcinoma , immunology
The histogenesis of synovial sarcomas remains controversial. An origin from epithelium, synovium, or synovial‐related cells and neural tissue has been advanced. Using a combination of a cytokeratin (epithelial marker) antibody and a vimentin (mesenchymal marker) antibody, this study suggests that a synovial sarcoma might be regarded as a carcinosarcoma. It also highlights the diagnostic utility of those antibodies in the diagnosis of synovial sarcomas.