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Acute leukemia occurring 19 years after treatment of acute lymphoblastic leukemia
Author(s) -
Reynoso Eduardo E.,
Keating Armand,
Baker Michael A.
Publication year - 1987
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19870601)59:11<1963::aid-cncr2820591121>3.0.co;2-c
Subject(s) - medicine , lymphoblastic leukemia , acute leukemia , leukemia , pediatrics , oncology , immunology
A 22‐year‐old woman presented with acute lymphoblastic leukemia (ALL) during pregnancy. She had been successfully treated for ALL at the age of 3 years and had received maintenance treatment for 11 years. Complete remission of 3 years or more is an important factor for long‐term survival and potential cure. Relapses may occur in the first 5 years after maintenance is discontinued. Later relapses are distinctly unusual. We have found six more cases of ALL occurring long after the initial remission in the English literature. It is unclear whether late relapse represents true relapse or a second leukemia. Life‐long followup of children with ALL may be necessary.