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Orchidectomy alone in stage I nonseminomatous testicular germ cell tumors
Author(s) -
Gelderman Willem A. H.,
Koops Heimen Schraffordt,
Sleijfer Dirk Th.,
Oosterhuis J. Wolter,
Marrink Jan,
De Bruijn Henk W. A.,
Oldhoff Jan
Publication year - 1987
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19870201)59:3<578::aid-cncr2820590337>3.0.co;2-j
Subject(s) - medicine , exploratory laparotomy , laparotomy , stage (stratigraphy) , chemotherapy , germ cell tumors , surgery , germ cell , general surgery , paleontology , biology , biochemistry , chemistry , gene
Fifty‐four patients with Stage I nonseminomatous testicular germ cell tumors (NSTGCT) were treated from 1982 to 1984. In 1982 and 1983, the orchidectomy was followed by an exploratory laparotomy to conclude the dissemination study. In 1984, laparotomy was performed only if indicated. The mean follow‐up was 29 months. A relapse occurred in 11 patients (20%). The relapse rate in patients who underwent exploratory laparotomy was as high as that in patients who did not. All patients treated for relapse by chemotherapy and surgery entered a complete remission for at least 1 year. It proved impossible to establish criteria for prediction of a subsequent relapse. Both serum tumor marker assays and roentgenography are important aids in diagnosing a relapse. With careful follow‐up of Stage I NSTGCT patients, a wait‐and‐see attitude can be adopted until a relapse occurs.