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Congenital leukemia with placental involvement: Report of a case with ultrastructural study
Author(s) -
Heras Jorge Las,
Leal Gabriel,
Daria Haust M.
Publication year - 1986
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19861115)58:10<2278::aid-cncr2820581020>3.0.co;2-p
Subject(s) - ultrastructure , placenta , chorionic villi , medicine , fetus , pathology , infiltration (hvac) , placenta diseases , leukemia , obstetrics , pregnancy , biology , immunology , physics , genetics , thermodynamics
The study of a stillborn infant and the placenta, showing extensive infiltration of fetal organs and chorionic villi by leukemic cells, is reported. The nature of the malignant cells was not apparent by light microscopic examination. Ultrastructural examination showed that these were inmature myeloblasts, stressing the usefulness of electron microscopic study in establishing the diagnosis. The current case study seems to be the first in the literature in which both placenta and fetus were studied in extenso.