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Metastatic interstitial pneumonitis after autologous bone marrow transplantation: A consequence of reinjection of malignant cells?
Author(s) -
Glorieux Philippe,
Bouffet Eric,
Philip Irène,
Biron Pierre,
Holzapfel Laurent,
Floret Daniel,
Bouvier Raymonds,
Vitrey Danielle,
Pinkerton Ross,
BrunatMentigny Maud,
Philip Thierry
Publication year - 1986
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19861101)58:9<2136::aid-cncr2820580929>3.0.co;2-j
Subject(s) - medicine , autopsy , interstitial pneumonitis , malignant lymphoma , bone marrow transplantation , bone marrow , transplantation , pathology , pneumonitis , lymphoma , lung , respiratory disease , surgery
Two cases of fatal interstitial pneumonitis developing after an autologous bone marrow transplantation are described. In both cases the autopsy revealed diffuse malignant pulmonary involvement. The first case involved a 4‐year‐old boy who had a Burkitt's lymphoma; the second case involved a 4‐year‐old girl with a neuroblastoma. The authors postulate that in these cases, the clinical picture may have been related to reinfusion of malignant cells.