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Mantle zone lymphoma with central nervous system involvement
Author(s) -
Bedotto John,
Spier Catherine M.,
Paquin Maria L.,
Grogan Thomas M.,
Ahmann Frederick R.,
Greenberg Bernard R.
Publication year - 1986
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19861101)58:9<2125::aid-cncr2820580927>3.0.co;2-t
Subject(s) - medicine , pathology , lymphocytosis , central nervous system , chronic lymphocytic leukemia , cerebrospinal fluid , lymphoma , mantle cell lymphoma , mantle zone , optic nerve , leukemia , anatomy , immunology , antibody , germinal center , b cell
A 68‐year‐old man with a 7‐year history of lymphocytosis and lymphadenopathy is described. Accelerated disease, indicated by bilateral optic nerve and cerebrospinal fluid involvement, prompted thorough histologic and immunologic assessment. Although initially believed to have chronic lymphocytic leukemia (CLL), results showed mantle zone lymphoma (MZL) with central nervous system (CNS) involvement. The authors believe that this represents the first case of MZL with CNS involvement.