Premium
The significance of the fibrin/fibrinogen degradation product in serum of carcinoma patients with hematogenous metastasis
Author(s) -
Imaoka Shingi,
Sasaki Yo,
Iwanaga Takeshi,
Terasawa Toshio
Publication year - 1986
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19861001)58:7<1488::aid-cncr2820580719>3.0.co;2-c
Subject(s) - medicine , fibrinogen , fibrinolysis , fibrin , metastasis , carcinoma , gastroenterology , surgery , cancer , immunology
Abstract Fibrin/fibrinogen degradation product (FDP) was measured in 270 cases with various carcinomas. An elevation of FDP (5 μg/ml or more) was observed in 68 cases (25%). Of the 68 elevated FDP cases, 56 (82%) were inoperable or received nonradical resection. Forty of those 56 cases (71%) showed hematogenous metastasis. FDP in those cases which showed hematogenous metastasis was found to be due to fibrinolysis accompanied by consumption coagulopathy.