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The integration of cytogenetic analysis into the evaluation of cryptic exudative effusions
Author(s) -
Meyers Frederick J.,
Lewis Jerry P.,
Marianos Stephen
Publication year - 1986
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19861001)58:7<1479::aid-cncr2820580717>3.0.co;2-g
Subject(s) - serous fluid , medicine , cytogenetics , karyotype , chromosome analysis , pathology , effusion , chromosome , biology , surgery , genetics , gene
Cytogenetic analysis of serous effusions is a proven method of distinguishing a malignant from a benign effusion. This article demonstrates that patient management can be altered because of the results of karyotyping. Because such analysis is not necessary in all cases, an algorithm is constructed that defines the place of cytogenetics in the orderly evaluation of exudative serous effusions. As Cytogenetic techniques improve, specific malignant cell types can be diagnosed based on cytogenetic abnormalities.