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Malignant schwannoma with a rhabdomyoblastic component, a so‐called triton tumor. A clinicopathologic study
Author(s) -
Dewit Luc,
AlbusLutter Cherry E.,
De Jong Antonius S. H.,
Voǔte Paul A.
Publication year - 1986
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19860915)58:6<1350::aid-cncr2820580628>3.0.co;2-9
Subject(s) - desmin , medicine , schwannoma , pathology , immunoperoxidase , myoglobin , staining , immunohistochemistry , vimentin , antibody , biology , monoclonal antibody , immunology , biochemistry
Triton tumors, malignant schwannomas with a rhabdomyoblastic component, are rare. This article reports the clinical course, therapeutic approach, and histopathplogic aspects of three cases. Immunoperoxidase staining for the Schwann' s cell marker S‐100 protein and for the skeletal muscle proteins desmin, myosin, and myoglobin proved to be useful for diagnosis. The clinical histories of 24 previously reported cases are analyzed, and the therapeutic possibilities are discussed.